Table 1.
Baseline characteristics
| Trans women (n = 8) | Trans men | ||
|---|---|---|---|
| With anastrozole (n = 8) | Without anastrozole (n = 10) | ||
| Age (years) | 26 (20-29) | 23 (20-26) | 22 (19-25) |
| BMI (kg/m2) | 22 ± 4 | 28 ± 8 | 25 ± 4 |
| MRS liver fat content (%) | 2.33 (1.07-2.92) | 1.41 (0.45-4.81) | 1.13 (0.60-1.68) |
| VAT (cm3) | 104 ± 74 | 86 ± 63 | 56 ± 36 |
| SAT (cm3) | 121 ± 73 | 289 ± 192 | 201 ± 94 |
| VAT/SAT ratio | 0.91 ± 0.06 | 0.31 ± 0.03 | 0.28 ± 0.04 |
| Estradiol (pmol/L) | 106 (93-149) | 133 (119-438) | 172 (109-446) |
| Testosterone (nmol/L) | 19.9 ± 3.4 | 1.3 ± 0.3 | 1.7 ± 0.6 |
| AST (U/L) | 26.0 ± 7.7 | 22.3 ± 6.7 | 20.6 ± 4.7 |
| ALT (U/L) | 25.1 ± 13.3 | 21.8 ± 14.5 | 21.2 ± 9.1 |
| Albumin (g/L) | 44.9 ± 2.5 | 43.1 ± 3.3 | 43.9 ± 4.3 |
| Cholesterol (mmol/L) | 4.4 ± 0.85 | 4.3 ± 0.4 | 4.5 ± 0.4 |
| HDL cholesterol (mmol/L) | 1.2 ± 0.2 | 1.3 ± 0.3 | 1.4 ± 0.3 |
| LDL cholesterol (mmol/L) | 2.7 ± 0.7 | 2.5 ± 0.4 | 2.7 ± 0.5 |
| Triglycerides (mmol/L) | 1.3 ± 0.5 | 1.2 ± 0.5 | 0.8 ± 0.2 |
| Glucose (mmol/L) | 4.0 ± 0.8 | 4.4 ± 0.7 | 3.9 ± 0.7 |
| Creatinine (µmol/L) | 78.6 ± 10.3 | 64.9 ± 8.5 | 62.0 ± 5.3 |
Baseline characteristics, displayed per study group.
Abbreviations: AST, aspartate transaminase; ALT, alanine transaminase; BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MRS, magnetic resonance spectroscopy; SAT, subcutaneous adipose tissue; VAT, visceral adipose tissue.
VAT and SAT are presented in mean volumes of the umbilicus and L2-3 slice (both 1 cm slice thickness).