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. 2023 Dec 6;43(4):616–632. doi: 10.1002/npr2.12403

TABLE 5.

Reported proportion of patients experiencing clinically significant improvements in anxiety and sleep quality after receiving treatment with cannabis‐based medicinal products (CBMPs).

PROM Follow‐up interval Oils Dried flower Oils and dried flower p‐Value
n (%) n (%) n (%)
GAD‐7 1 month 142 (22.15) 94 (40.00) 169 (33.67) <0.001***
GAD‐7 3 months 143 (22.31) 92 (39.15) 178 (35.46) <0.001***
GAD‐7 6 months 143 (22.31) 90 (38.30) 181 (36.06) <0.001***
GAD‐7 12 months 138 (21.53) 93 (39.57) 175 (34.86) <0.001***
SQS 1 month 144 (22.46) 75 (31.91) 161 (32.07) <0.001***
SQS 3 months 153 (23.87) 76 (32.34) 170 (33.86) <0.001***
SQS 6 months 155 (24.18) 84 (35.74) 180 (35.86) <0.001***
SQS 12 months 154 (24.02) 80 (34.04) 176 (35.06) <0.001***

Note: Clinically significant improvements in GAD‐7 and SQS were assessed at regular intervals, and the data were analyzed using the chi‐squared test.

Abbreviations: GAD‐7, generalized anxiety disorder‐7; n, number of patients; PROM, patient‐reported outcome measures; SQS, Single‐Item Sleep Quality Scale.

*

p < 0.050;

**

p < 0.010;

***

p < 0.001.