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New model for ATF6α oligomer. (A) New model to explain the structures of dimer and oligomer produced from ATF6α WT, C467A, C618A, and C467&618A. (B) Immunoblotting using anti-ATF6α antibody of cell lysates prepared from WT and DKO HCT116 cells and then subjected to reducing (R) and non-reducing (NR) SDS-PAGE. (C) Schematic representation of C618-dimer and C467-dimer in SDS-containing buffer. (D) Model to explain the difference in migration speed between C618-dimer and C467-dimer.
