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. 2020 Apr 9;45(1):57–64. doi: 10.1247/csf.20007

Table I.

Examples of studies on acentrosomal somatic cells

Species/cell Approach Main finding Reference
Monkey/CVG-2 Laser microsurgery A bipolar mitotic spindle is formed in the absence of centrosomes. Khodjakov et al., 2000
Fly Mutant of DSas-4 Centrosomes are not necessary for the development of the fly. Basto et al., 2006
Monkey/BSC-1 Needle microsurgery The fidelity of the bipolar mitotic spindle is highly compromised in the absence of centrosomes. Hornick et al., 2011
Chicken/DT40 Knockout of CEP152/STIL Centrosome loss leads to delays in spindle formation and high rates of chromosomal instability. Sir et al., 2013