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. 2023 Dec 1;27(1):44. doi: 10.3892/etm.2023.12332

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Copyright: © Cheng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Changes in NLRP3 inflammasome components upon emodin treatment. (A-D) Representative immunofluorescence staining images and quantitative analysis of spinal NLRP3 and caspase-1 in the control, CFA and CFA + emodin groups. Scale bar, 20 µm. (E) Representative western blots and (F) quantitation examination of NLRP3 and cleaved caspase-1 expression levels the in spinal cords of the control, CFA and CFA + emodin groups. Data are presented as the mean ± SD (n=5). ^*P<0.05 vs. control group, ^#P<0.05 vs. CFA group. NLRP3, Nod-like receptor family pyrin domain-containing 3; CFA, complete Freund's adjuvant.