Figure 2.
Sample distribution and diagnostic performance of mNGS and culture. (A) Distribution of samples. Each column of sticks represents a single patient. Blue and orange sticks represent positive and negative results, respectively; (B) Comparison of positive rates between mNGS and culture, and CMT, in a pairwise manner. (C) Concordance of mNGS and culture results. (D) Detecting performance at the pathogen level. The culture in (B–D) included BALF, sputum and blood culture results. Specifically, a positive culture result refers to at least one culture is positive, and a negative culture result means all cultures were negative. p-value was calculated with McNemar-test. *p<0.05, ***p<0.001; # rare infection.