TABLE 3.

Differences between newly determined sequence and published sequence

Sequence location in gap Da	Gene	Sequence comparison
		Publishedb	This work
2278–2280	ccaR upstream	cc	ccc
2356–2358	ccaR upstream	cc	ccc
2450–2451	ccaR upstream	a	aa
3502–3503	orf11 upstream	c	cc
3513	orf11 upstream	gg	g
3643–3645	orf11 upstream	ccg	cgc
3729–3730	orf11 upstream	gg	gc
5754–5756	blp downstream	cc	ccc
5761–5764	blp downstream	ggg	gggg
5790–5791	blp downstream	g	gg
5803–5804	blp downstream	c	cc

^aNucleotide 7 represents the first base of new sequence adjacent to cefF published sequence (30). 

^bSequence determined by Pérez-Llarena et al. (44) for wild-type S. clavuligerus ATCC 27064.