Table A6.
Comparison of the internal and external data for the identified predictor variables. Values are presented as number (%) of patients or the median (IQR), day of start antibiotic therapy on the ICU (d0).
| Variables | External Data (N = 150) |
Internal Data (N = 376) |
p-Value |
|---|---|---|---|
| Sex (male) | 97 (64.7%) | 232 (61.7%) | 0.59 |
| Age (years) | 62.0 [54.0, 70.0] | 64.0 [56.0, 71.0] | 0.36 |
| Serum creatinine d0 (mg/dL) | 0.77 [0.57, 1.04] | 0.995 [0.69, 1.56] | <0.001 |
| Type of antibiotic | <0.001 | ||
| Amoxicillin | 9 (6.0%) | 15 (4.0 %) | |
| Cefotaxime | 0 | 77 (20.5 %) | |
| Ceftazidime | 6 (4.0%) | 15 (4.0 %) | |
| Ceftriaxone | 21 (14.0%) | 112 (29.8 %) | |
| Cefuroxime | 0 | 72 (19.1 %) | |
| Flucloxacillin | 0 | 17 (4.5 %) | |
| Meropenem | 77 (51.3%) | 54 (14.4 %) | |
| Piperacillin/tazobactam | 37 (24.7%) | 14 (3.7 %) |