Table 2.
Gut AMPs in synergy with conventional antibiotics.
| Gut AMPs | Antibiotics | Target | References |
|---|---|---|---|
| Nisin | Ramoplanin | MRSA | [74] |
| Polymyxin E Clarithromycin | P. aeruginosa | [75] | |
| Amoxicillin Penicillin Streptomycin Ceftiofur Tetracycline |
S. suis | [65] | |
| Nisin Z | Ampicillin Chloramphenicol Kanamycin Lincomycin Penicillin G Rifampicin Streptomycin Tetracycline Vancomycin |
P. fluorescens LRC-R73 and its Penicillin-resistant/Streptomycin-resistant/Lincomycin-resistant/Rifampicin-resistant variant | [63] |
| Lacticin 3147 | Polymyxin B | S. aureus 5247 | [76] |
| Actagardine | Ramoplanin Metronidazole Vancomycin |
C. difficile | [77] |
| Thuricin CD | Ramoplanin | C. difficile | [77] |
| Vancomycin | C. difficile | [77] | |
| Subtilosin A | Clindamycin phosphate Metronidazole |
G. vaginalis | [66] |
| Lauramide arginate Ester poly-lysine |
G. vaginalis | [66] | |
| PsVP-10 | Chlorhexidine |
S. mutans
S. sobrinus |
[78] |
| Plantaricin E, F, J, K | Several antibiotics | C. albicans | [79] |
| Colistin | Tobramycin | P. aeruginosa | [73] |
| Cryptdin 2 | Ampicillin | S. typhimurium | [68] |
| Laterosporulin10 | Rifampicin | M. tuberculosis H37Rv | [62] |
| Colistin | Azithromycin |
A. baumannii
K. pneumoniae P. aeruginosa |
[71] |
| LL-37 | Azithromycin |
A. baumannii
K. pneumoniae P. aeruginosa |
[71] |
| Human defensin 5 (HD5) |
Meropenem | C. difficile | [67] |
| Human neutrophil peptide-1 (HNP1) | Rifampicin | M. tuberculosis H37Rv | [69] |
| Human β-defensin 3 (HBD3) |
Meropenem Moxifloxacin Piperacillin-Tazobactam Tigecycline |
C. difficile | [67] |