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Possible modes of neuroprotective/cytoprotective action of HN and HN analogues. (A) Triggering of intracellular cell rescue mechanisms after interaction with cell membrane HN receptors and/or specific intracellular HN partners (the symbol “???” represents unknown putative mechanisms of secretion and/or entry into cells). (B) Inhibiting the formation of toxic Aβ fibrils in the extracellular space.
