Table 5.

Linear regression between VAI and clinical and biochemical characteristics of the PCOS women according to phenotypes during the follow-up.

		Phenotype A (n = 233) $\mathsf{\beta }$ (95% CI)	p-Value	Phenotype B (n = 36) $\mathsf{\beta }$ (95% CI)	p-Value	Phenotype C (n = 20) $\mathsf{\beta }$ (95% CI)	p-Value	Phenotype D (n = 21) $\mathsf{\beta }$ (95% CI)	p-Value
Clinical Characteristics	Follow-up (months)	0.003 (−0.001–0.007)	0.077	0.001 (−0.010–0.011)	0.980	−0.002 (−0.013–0.008)	0.661	−0.006 (−0.017–0.006)	0.285
	F-G Score	0.003 (−0.037–0.044)	0.891	0.005 (−0.099–0.112)	0.909	−0.065 (−0.254–0.125)	0.485	0.234 (−0.085–0.553)	0.129
Hormonal Profile	17OHP *	−0.130 (−0.452–0.192)	0.426	−0.565 (−1.565–0.436)	0.252	−0.015 (−1.563–1.532)	0.983	−0.246 (−3.726–3.234)	0.868
	Testosterone	−0.007 (−0.016–0.001)	0.100	0.003 (−0.028–0.034)	0.854	0.018 (−0.030–0.066)	0.435	−0.087 (−0.145–−0.029)	0.009
	SHBG	−0.005 (−0.010–0.001)	0.103	−0.007 (−0.022–0.009)	0.407	−0.022 (−0.049–0.004)	0.096	−0.035 (−0.058–−0.011)	0.009
	Calculated free testosterone	−0.001(−0.012–0.010)	0.845	0.027 (−0.038–0.091)	0.388	0.064 (0.003–0.125)	0.041	−0.069 (−0.332–0.194)	0.563
	DHEAS	−0.001 (−0.001–−0.001)	0.001	−0.001 (−0.001–0.001)	0.155	0.001 (−0.001–0.001)	0.251	−0.001 (−0.002–0.001)	0.121
	Androstenedione	−0.145 (−0.326–0.039)	0.116	−0.399 (−0.837–0.039)	0.072	0.623 (−0.400–1.646)	0.211	−0.264 (−0863–0.336)	0.333
Obesity Classification	Normal	−1.512 (−2.163–−0.862)	0.001	−1.517 (−3.748–0.714)	0.175	−1.902 (−3.657–0.146)	0.035	−1.478 (−2.529–−0.426)	0.012
	Overweight	0.128 (−0.400–0.656)	0.634	−0.737 (−2.177–0.704)	0.304	0.197 (−0.188–4.182)	0.071	1.178 (−0.528–2.885)	0.150
	Obesity	−0.019 (−0.081–0.042)	0.526	0.082 (−0.119–0.283)	0.398	−0.074 (−0.737–0.590)	0.774	1.152 (−1.285–3.588)	0.307
Metabolic Syndrome Evaluation (ATP III)	Metabolic syndrome	1.671 (1.370–1.972)	0.001	1.369 (0.565–2.173)	0.002	2.772 (1.883–3.661)	0.001	0.323 (−0.828–1.474)	0.536
Diagnosis of Metabolic Changes	Total glucose intolerance	0.925 (0.463–1.388)	0.001	0.736 (−0.469–1.942)	0.221	1.686 (0.234–3.138)	0.025	−0.006 (−1.573–1.561)	0.993
	Total T2DM	2.369 (1.586–3.153)	0.001	1.410 (−0.552–3.372)	0.152	6.409 (3.183–9.636)	0.001	0.885 (−1.625–3.394)	0.440
Metabolic Profile	Total cholesterol	0.007 (−0.001–0.014)	0.053	0.029 (0.012–0.046)	0.002	0.022 (0.005–0.039)	0.013	−0.006 (−0.038–0.025)	0.665
	LDL-c	0.006 (−0.002–0.014)	0.123	0.035 (0.014–0.056)	0.002	0.030 (0.010–0.050)	0.006	−0.002 (−0.038–0.033)	0.882
	G0′	0.032 (0.018–0.046)	0.001	−0.001 (−0.019–0.018)	0.965	0.053 (−0.040–0.145)	0.247	0.014 (−0.017–0.045)	0.325
	G120′	0.019 (0.014–0.024)	0.001	0.019 (0.005–0.033)	0.010	0.026 (0.002–0.051)	0.036	0.007 (−0.052–0.065)	0.772
	I0′	0.037 (0.022–0.053)	0.001	0.020 (−0.030–0.071)	0.421	0.111 (−0.034–2.56)	0.125	0.108 (−0.046–0.626)	0.137
	I120′	0.005 (0.003–0.006)	0.001	0.005 (−0.003–0.013)	0.194	0.017 (0.005–0.029)	0.008	0.024 (−0.051–0.099)	0.154
	HbA1C	0.721 (0.383–1.059)	0.001	0.071 (−0.392–0.535)	0.754	0.320 (−3.006–3.647)	0.836	0.311 (−0.813–1.435)	0.534
	HOMA-IR	0.178 (0.123–0.233)	0.001	0.206 (0.038–0.374)	0.018	0.227 (−0.143–0.597)	0.214	−0.001 (−0.270–0.268)	0.993
	QUICKI	−22.34 (−28.46–−16.21)	0.001	−31.04 (−52.37–−9.71)	0.006	−22.41 (−48.13–3.30)	0.084	−15.27 (−30.06–−0.48)	0.044
	ISI Matsuda	−0.252 (−0.351–−0.153)	0.001	0.0769 (−0.498–0.652)	0.781	−0.331 (−0.619–−0.436)	0.027	−0.256 (−2.096–1.583)	0.327

* Adrenal enzymatic deficiency was excluded by cortrosyn test.