Figure 3.

(A) The structures of isolated piceatannol and scirpusin B. Effects of piceatannol and scirpusin B on (B) acetylcholinesterase inhibition, (C) anti-amyloid-β_1-42 peptide aggregations, (D) and neuroprotective activities against amyloid-β_25-35 peptide (40 μg/mL)-induced cell death in SH-SY5Y cell models; the blank was a 0.1% DMSO addition, and the control was a (0.1%DMSO + 40 μg/mL amyloid-β_25-35 peptide) addition. IC₅₀ represents the concentrations for 50% inhibition in the present study. Student’s t-test was used to compare neuroprotective activities between the control versus each sample treatment or the control versus the blank. It was considered a statistically significant difference when p < 0.01 **, or p < 0.001 ***.