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The expression of ISGs are significantly down-regulated in the corneas of TRPM8−/− mice compared with levels in WT mice. (A) Top 10 terms of the GO biological process enrichment analysis of DEGs. (B) Heatmap illustrating the significantly down-regulated ISGs in DEGs. (C) The qPCR validation of partial ISG expression was conducted. *P < 0.05; **P < 0.01; ***P < 0.001.
