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Schematic diagram of anti-inflammatory properties of OC in LPS-induced inflammation. COX-2 (Cyclooxygenase-2); ERK (Extracellular Signal-Regulated Kinase); IL-6 (Interleukin-6); LPS (Lipopolysaccharide); MAPKs (Mitogen-Activated Protein Kinases); MIP-1α (Macrophage Inflammatory Protein-1 alpha); NOS2 (Nitric Oxide Synthase 2); OC (Oleocanthal); p38 (p38 Mitogen-Activated Protein Kinase); TLR4 (Toll-like receptor 4); TNF-α (Tumor Necrosis Factor-alpha); Ub (Ubiquitin).
