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. 2023 Dec 13;11(12):3296. doi: 10.3390/biomedicines11123296

Table 1.

Demographics and clinical characteristics, presented as medians (ranges) or numbers (percents). Abbreviations: GC gauze compresses, MAD mucosal atomization device, NRS numeric rating scale, PDPH postdural puncture headache.

Variables Total
(n = 15 Patients)
GC Group
(n = 4 Patients)
Second-Line
MAD Group
(n = 3 Patients)
MAD Group
(n = 8 Patients)
Age (years) 32 (24 to 40) 30 (26 to 40) 34 (24 to 36) 33 (29 to 40)
Body weight (kg) 71 (57 to 179) 80 (58 to 179) 80 (60 to 140) 71 (57 to 95)
Height (cm) 163 (158 to 182) 161 (158 to 170) 160 (160 to 160) 170 (150 to 182)
Body mass index (kg/m2) 27 (21 to 70) 29 (22 to 70) 31 (23 to 55) 25 (21 to 32)
Risk factors for PDPH
 Age 20–30 years 6 (40%) 3 (75%) 1 (33%) 2 (25%)
 Body mass index < 20 kg/m2 0 (0.0%) 0 (0.0%) 0 (0.0%) 0 (0.0%)
 History of headache/migraine 3 (20%) 1 (25%) 1 (33%) 1 (13%)
 History of PDPH 3 (20%) 1 (25%) 1 (33%) 1 (13%)
Neuraxial technique
 Spinal anesthesia 8 (53%) 2 (50%) 2 (67%) 4 (50%)
 Epidural anesthesia 5 (33%) 0 (0.0%) 1 (33%) 4 (50%)
 Both a 2 (13%) 2 (50%) 0 (0.0%) 0 (0.0%)
Time from puncture to PDPH onset (days) 1.0 (0.0 to 3.0) 1.5 (1.0 to 3.0) 1.0 (1.0 to 1.0) 1.5 (0.0 to 3.0)
Pain intensity at time of PDPH diagnosis (NRS score) 7 (2 to 10) 7 (5 to 10) 6 (3 to 10) 8.5 (2 to 10)
PDPH-associated symptoms
 Neck stiffness/pain 12 (80%) 4 (100%) 2 (67%) 6 (75%)
 Tinnitus/hearing loss 3 (20%) 0 (0.0%) 0 (0.0%) 3 (38%)
 Photophobia 1 (6.7%) 0 (0.0%) 0 (0.0%) 1 (13%)
 Nausea/vomiting 4 (27%) 2 (50%) 0 (0.0%) 2 (25%)
Conservative treatment
 Oral/IV fluid intake 9 (60%) 3 (75%) 1 (33%) 5 (63%)
 Caffeine 12 (80%) 3 (75%) 3 (100%) 6 (75%)
 Ibuprofen 12 (80%) 3 (75%) 3 (100%) 6 (75%)
 Paracetamol 8 (53%) 2 (50%) 1 (33%) 5 (63%)

a Two patients received spinal anesthesia for secondary cesarean section after failed epidural attempts or after epidural anesthesia with insufficient pain relief.