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In-clinic cross-matching – microscopic appearance. (a) Microscopic appearance of rouleaux, in which the RBCs resemble stacks of coins; this is not of clinical concern and does not indicate a cross-match incompatibility. (b) Microscopic appearance of agglutination showing a disorganised mass of RBCs in clumps, indicating an incompatible cross-match reaction. Images courtesy of Nic llchyshyn, Dick White Referrals, Six Mile Bottom, UK
