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. 2020 Oct 7;23(6):526–533. doi: 10.1177/1098612X20961350

Table 2.

Copper scoring system for qualitative copper assessment modified from a scoring system in dog liver biopsy specimens 26

Score Accumulation of copper granules in hepatocytes or macrophages
0 No copper granule accumulation
1 Variable copper granules
2 Small-to-moderate numbers of copper granules
3 Moderate-to-large numbers of copper granules in 50–75% of hepatocytes; copper-containing macrophages may be present
4 Moderate-to-large numbers of copper granules in >75% of hepatocytes; copper-containing macrophages may be present
5 Panlobular presence of copper granules, usually associated with copper-containing macrophages
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