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. 2023 Dec 6;96(4):1515–1528. doi: 10.3233/JAD-230680

Table 2.

Baseline levels of cerebrospinal fluid (CSF) biomarkers

Variable	SSVD (n = 38)	AD (n = 121)	Mixed dementia (n = 62)	Control (n = 96)	p between groups
Aβ₄₂ (ng/L)	593 (425–700)^a,f	386 (314–500)^d	395 (318–486)^d	658 (500–870)	<0.001
t-tau (ng/L)	319 (240–408)^e,f	610 (420–840)^d	700 (460–873)^d	245 (170–359)	<0.001
p-tau₁₈₁ (ng/L)	49 (37–61)^e,f	82 (62–113)^d	80 (61–103)^d	47 (34–61)	<0.001
NFL (ng/L) ^#	1109 (921–2217)^d	1119 (848–1533)^c,d	1464 (949–1889)^d	701 (505–863)	<0.001
sAβPPα (ng/mL)	233 (170–290)^a,e,f	301 (230–378)	293 (235–422)	306 (221–369)	<0.001
sAβPPβ (ng/mL)	371 (286–462)^d,e,f	568 (410–739)	551 (405–803)	526 (400–676)	<0.001
CSF/serum albumin ratio	7.2 (5.3–9.2)^a,b	5.4 (4.4–7.7)	6.4 (5.0–8.6)^a	5.6 (4.8–7.0)	0.01