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. 2023 Dec 12;15(24):5809. doi: 10.3390/cancers15245809

Table 4.

Univariate logistic regression analyses for poor QOL.

Variables OR 95% CI p
Sociodemographic
 Age ≥ 50 years 1.263 0.418–3.815 0.679
 No spouse 0.968 0.272–3.446 0.960
 Education < high school 1.584 0.524–4.790 0.415
 No religion 1.062 0.362–3.111 0.913
 Not employed 1.152 0.399–3.327 0.794
 Monthly income < $2000 2.065 0.713–5.986 0.182
 Menopausal 3.896 0.467–32.374 0.209
 Having comorbidity 4.889 1.590–15.028 0.006
Clinical
 Stage 2–3 (ref. stage 0–1) 1.875 0.625–5.629 0.262
 MRM (ref. BCS) 3.015 0.991–9.175 0.052
 Receiving chemotherapy 2.209 0.572–8.540 0.251
 Receiving radiation therapy 0.547 0.181–1.651 0.284
 Receiving anti-hormone therapy 1.021 0.289–3.601 0.974
Lifestyle
Year 1 Exercises regularly 1.015 0.037–3.356 0.980
Smokes 1.167 0.214–6.348 0.858
Drinks 0.313 0.037–2.653 0.287
Year 2 Exercises regularly 1.128 0.372–3.425 0.831
Smokes 7.600 0.645–89.574 0.107
Drinks 0.557 0.111–2.782 0.476
Year 3 Exercises regularly 0.871 0.280–2.709 0.811
Drinks 0.677 0.169–2.705 0.581
Symptoms
Year 1 Fatigue 1.603 0.479–5.367 0.444
Nausea/vomiting 2.399 0.777–7.409 0.128
Pain 2.647 0.900–7.790 0.077
Dyspnea 3.594 1.208–10.688 0.021
Insomnia 5.889 1.840–18.845 0.003
Appetite loss 1.765 0.151–20.658 0.651
Diarrhea 1.783 0.526–6.040 0.353
Financial difficulties 1.000 0.350–2.586 >0.999
Anxiety 3.594 1.208–10.688 0.021
Depression 2.507 0.837–7.504 0.100
Year 2 Fatigue 13.520 3.938–46.423 <0.001
Nausea/vomiting 2.600 0.790–8.555 0.116
Pain 5.923 1.918–18.295 0.002
Dyspnea 2.263 0.776–6.599 0.135
Insomnia 3.747 1.149–12.221 0.028
Appetite loss 6.000 0.919–39.185 0.061
Diarrhea 2.000 0.582–6.867 0.271
Financial difficulties 2.037 0.697–5.953 0.193
Anxiety 7.361 2.290–23.664 0.001
Depression 7.286 2.307–23.010 0.001
Year 3 Fatigue 8.281 2.518–27.231 0.001
Nausea/vomiting 4.636 1.497–14.361 0.008
Pain 4.924 1.620–14.996 0.005
Dyspnea 5.923 1.918–18.275 0.002
Insomnia 7.467 2.130–26.172 0.002
Appetite loss 12.200 1.184–125.717 0.036
Diarrhea 1.190 0.332–4.271 0.789
Financial difficulties 2.120 0.732–6.136 0.166
Anxiety 3.769 1.245–11.414 0.019
Depression 7.361 2.290–23.664 0.001

QOL, quality of life, CI = confidence interval, OR = odds ratio, MRM = modified radical mastectomy, BCS = breast-conserving surgery.