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. 2023 Dec 17;11(12):3333. doi: 10.3390/biomedicines11123333
AAV adeno-associated virus
AD Alzheimer’s disease
ALS amyotrophic lateral sclerosis
BBB blood brain barrier
CSPG chondroitin sulfate proteoglycans
CNS central nervous system
CRISPR/Cas clustered regularly interspaced short palindromic repeats/CRISPR-associated protein
crRNA crisprRNA
DAM disease-associated microglia
DAMP damage-associated molecular patterns
DRG dorsal root ganglion
DSB double-strand break
IDLV integrase-deficient lentivirus
ECM extracellular matrix
HR homologous recombination
LV lentivirus
MAG myelin-associated glycoprotein
MBP myelin basic protein
MCT monocarboxylate transporter
MSA multiple system atrophy
MS multiple sclerosis
NAMP neurodegeneration-associated molecular patterns
NDD neurodegenerative disorder
NHEJ non-homologous end joining
OPC oligodendrocyte precursor cell
ORF open reading frame
PAM protospacer adjacent motif
PAMP pathogen-associated molecular patterns
PD Parkinson’s disease
PNS peripheral nervous system
PRR pattern recognition receptors
RGMa repulsive guidance molecule A
RNP ribonucleoprotein complex
sgRNA single guide RNA
TALEN transcription activator-like effector nuclease
TLR Toll-like receptor
VLP virus-like particle
ZNF zinc finger nuclease