AAV |
adeno-associated virus |
AD |
Alzheimer’s disease |
ALS |
amyotrophic lateral sclerosis |
BBB |
blood brain barrier |
CSPG |
chondroitin sulfate proteoglycans |
CNS |
central nervous system |
CRISPR/Cas |
clustered regularly interspaced short palindromic repeats/CRISPR-associated protein |
crRNA |
crisprRNA |
DAM |
disease-associated microglia |
DAMP |
damage-associated molecular patterns |
DRG |
dorsal root ganglion |
DSB |
double-strand break |
IDLV |
integrase-deficient lentivirus |
ECM |
extracellular matrix |
HR |
homologous recombination |
LV |
lentivirus |
MAG |
myelin-associated glycoprotein |
MBP |
myelin basic protein |
MCT |
monocarboxylate transporter |
MSA |
multiple system atrophy |
MS |
multiple sclerosis |
NAMP |
neurodegeneration-associated molecular patterns |
NDD |
neurodegenerative disorder |
NHEJ |
non-homologous end joining |
OPC |
oligodendrocyte precursor cell |
ORF |
open reading frame |
PAM |
protospacer adjacent motif |
PAMP |
pathogen-associated molecular patterns |
PD |
Parkinson’s disease |
PNS |
peripheral nervous system |
PRR |
pattern recognition receptors |
RGMa |
repulsive guidance molecule A |
RNP |
ribonucleoprotein complex |
sgRNA |
single guide RNA |
TALEN |
transcription activator-like effector nuclease |
TLR |
Toll-like receptor |
VLP |
virus-like particle |
ZNF |
zinc finger nuclease |