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. 2023 Dec 13;12(24):2830. doi: 10.3390/cells12242830

Figure 1.

Figure 1

Adenovirus Survivin-Sodium Iodide Symporter (Ad-Sur-NIS) System. It is a gene-based bioimaging tool to differentiate between LM and LMS in women with suspicious uterine masses. Uterine LMS and LM cannot be differentiated using current imaging techniques. Survivin is increased in LMS, but not in LM. Using Ad-SUR-NIS, we were able to detect NIS in the presence of Survivin. NIS enables the uptake of F18-NaBF4 to cells, which leads to the visualization and identification of uterine LMS, but not LM.