Table 1.
Key clinical data of patients from whom PDAC PDX models were established.
| PDX ID | Gender | Age | Histology | TNM/Grading | Kras Mutation | Classification |
|---|---|---|---|---|---|---|
| 9553 | F | 67 | PDAC | pT3 N1/G3 | G12D | Primary |
| 9699 | M | 70 | PDAC | pT3 pN1 L1 V1 Pn1/G3 | G12V | Primary |
| 9759 | M | 61 | PDAC | pT3 pN1 L1 V0 Pn1 R1/G3 | G12R | Primary |
| 9996 | F | 60 | PDAC | pT3 pN1/G3 | wildtype | Primary |
| 10713 | M | 64 | PDAC | pT4 N1/G3 | G12D | Primary |
| 10953 | F | 61 | PDAC | pT3 N1/G2 | G12R | Primary |
| 10991 | F | 72 | PDAC | pT3 N1/G3 | G12V | Primary |
| 11056 | M | 77 | PDAC | pT3 N1/G2 | G12D | Primary |
| 11074 | F | 76 | PDAC | pT3 N0/G3 | Q61H | Primary |
| 11159 | M | 76 | PDAC | pT3 N1/G3 | wildtype | Primary |
| 11344 | M | 69 | PDAC | pT3 N1/G3 | G12V | Primary |
| 11495 | F | 51 | PDAC | pT3 N1/G3 | G12V | Primary |
| 12529 | F | 53 | PDAC | pT4 pN2 M1, Stage IV/G1 | G12V | Liver met |
| 12531 | M | 54 | PDAC | pT4 pN1 M1, Stage IV | wildtype | Liver met |
| 12532 | F | 72 | PDAC | pT4 pN1 M1, Stage IV | G12D | Liver met |
| 12534 | F | 71 | PDAC | pT3 N1 M1/G3 | wildtype | Primary |
| 12535 | M | 46 | PDAC | pT3 N0 M1 | wildtype | Primary |
| 12536 | F | 69 | PDAC | pT3 pN1 M0, Stage IV | Q61H, T58I | Primary |
| 12556 | M | 67 | PDAC | pT3 N1 M0, Stage IIB | G12V | Primary |
| 12558 | M | 56 | PDAC | pT3 N1 M0, Stage IIB | G12D | Primary |
| 12559 | M | 60 | PDAC | pT3 N1 M0, Stage IIB | G12D | Primary |
| 12560 | F | 82 | PDAC | pT3 N0 M0, Stage IIA | G12R | Primary |
| 12561 | F | 80 | PDAC | pT3 N1 M0, Stage IIB | G12R | Primary |
| 12650 | M | 48 | IPMN * | pT3 N0 M0, Stage IIA | G12D | Primary |
| 12706 | F | 82 | IPMN * | pT3 N0 M0, Stage IIA | G12V | Primary |
| 12707 | M | 60 | PDAC | pT3 N1 M0, Stage IIB | G12V | Primary |
| 12708 | F | 56 | PDAC | pT3 N1 M0, Stage IIB | G12D | Primary |
| 12709 | F | 51 | PDAC | pT3 N1 M0, Stage IIB | G12D | Primary |
| 12911 | M | 67 | PDAC | pT3 N0 M0, Stage IIA | G12V | Primary |
| 12912 | M | 67 | PDAC | pT3 N1 M0, Stage IIB | G12D | Primary |
| 12975 | F | 75 | IPMN * | pT3 N0 M0, Stage IIA | G12R | Primary |
| 12976 | F | 65 | PDAC | pT3 N1 M0, Stage IIB | G12D | Primary |
| 12958 | M | 83 | PDAC | pT3 N1 M0 | G12R | Primary |
| 12959 | M | 44 | PDAC | pT3 N1 M0 | G12D | Primary |
| 14044 | M | 65 | PDAC | pT3 N0 M1 L1 | G12V | Primary |
| 14476 | M | 65 | PDAC | pT3 N1 L0 | Q61K | Primary |
| 14741 | M | 50 | PDAC | pT2 N1 L0 | wildtype | Primary |
| 14912 | M | 73 | PDAC | pT2 N1 L1 | wildtype | Primary |
| 14954 | F | 63 | PDAC | pT2 N0 L0 | n/a | Primary |
| 14984 | M | 50 | PDAC | pT3 N1 L0 | Q61H | Primary |
| 14997 | M | 64 | PDAC | pT2 N1 L1 | wildtype | Primary |
| 14998 | M | 75 | PDAC | pT2 N0 L0 | n/a | Primary |
| 14691 | M | 65 | PDAC | pT3 N1 M0/G2 | wildtype | Primary |
| 14710 | F | 68 | IPMN * | pT3 N0 M0/G3 | G12D | Primary |
| 14847 | M | 80 | PDAC | pT3 N1 M0 L1/G3 | wildtype | Primary |
* Associated with invasive ductal adenocarcinoma; n/a—not available.