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. 2023 Dec 15;11(12):3323. doi: 10.3390/biomedicines11123323

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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No correlation between anti-hypertensive effects and endothelial function improvement (FMD) upon short-term ACEi treatment in hypertensive patients. Newly identified hypertensive patients were enrolled in the study at the outpatient facility of the Department of Neurology. Increases in flow-mediated dilation (FMD) were plotted as the function of the decrease in systolic blood pressure before and after enalapril (panel (A)) and lisinopril (panel (B)) treatments. Each symbol represents an individual patient. The correlation between the parameters was tested by Spearman’s test. Correlations were characterized statistically by the rho and p values. Correlation is considered to be significant when p < 0.05.