Table 2.

ΔS drug sensitivity for compounds affecting the PI3K/AKT/mTOR pathway, sorted by the ΔS mean from all four PNF1 cell lines.

PI3KCA			AKT1			MTOR
Compound	ΔS Mean	ΔS Variance	Compound	ΔS Mean	ΔS Variance	Compound	ΔS Mean	ΔS Variance
GNE-490	−0.66	0.25	Triciribine-PO4	−1.51	0.81	WYE-354	−0.53	1.15
NIBR-17	−0.48	0.14	A-443654	−0.82	0.04	AZD-2014	−0.34	0.24
PIK-90	−0.45	0.01	AT-7867	−0.62	0.16	GDC-0980	−0.24	0.14
BKM-120	−0.33	0.47	AZD-5363	−0.36	0.10	KU-0063794	−0.23	0.04
PF-04691502	−0.31	0.20	GDC-0068	−0.34	0.12	AZD-8055	−0.22	0.38
GNE-493	−0.28	0.08	H-89	−0.26	0.12	WAY-600	−0.20	0.19
PIK-93	−0.28	0.23	MK-2206	−0.13	0.02	PP-242	−0.20	0.89