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. 2023 Dec 18;11(12):3348. doi: 10.3390/biomedicines11123348

Table 4.

Stability of NLC-CUR at 0, 15, 30, 60, 90, and 120 days, at temperatures of 4 °C, 25 °C, and 37 °C.

Time (Days) Temperature (°C) Size (d. nm) PDI Zeta Potential (mV) EE (%) pH
0 4 212.85 ± 1.99 0.28 ± 0.04 −25.65 ± 0.93 92.45 7.00
25 212.54 ± 1.27 0.29 ± 0.02 −26.70 ± 1.17 92.90 7.13
37 211.09 ± 1.92 0.28 ± 0.09 −25.60 ± 0.12 92.5 7.11
15 4 210.43 ± 2.09 0.30 ± 0.02 −26.10 ± 2.01 90.66 7.12
25 209.70 ± 2.53 0.30 ± 0.02 −26.02 ± 0.19 92.80 7.12
37 214.90 ± 1.98 0.28 ± 0.02 −27.41 ± 2.01 92.49 7.19
30 4 220.30 ± 1.72 0.29 ± 0.01 −25.63 ± 2.08 90.12 7.09
25 221.62 ± 1.86 0.29 ± 0.02 −25.75 ± 1.67 92.77 7.19
37 230.08 ± 1.09 0.28 ± 0.02 −26.46 ± 1.03 91.7 7.07
60 4 229.54 ± 0.19 0.29 ± 0.03 −25.89 ± 0.21 90.1 7.00
25 231.62 ± 1.95 0.29 ± 0.04 −28.50 ± 1.19 92.34 6.98
37 228.90 ± 2.09 0.28 ± 0.09 −27.34 ± 0.94 91.56 7.01
90 4 231.45 ± 1.09 0.28 ± 0.07 −27.98 ± 2.02 90.04 7.05
25 228.53 ± 1.74 0.29 ± 0.01 −28.94 ± 2.14 91.54 6.85
37 231.45 ± 2.09 0.28 ± 0.01 −26.65 ± 1.98 90.08 6.98
120 4 230.10 ± 1.04 0.29 ± 0.09 −27.50 ± 1.84 90.05 7.01
25 231.90 ± 2.11 0.29 ± 0.08 −28.40 ± 1.12 91.29 7.01
37 232.43 ± 2.01 0.28 ± 0.08 −26.70 ± 0.17 90.02 6.87