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. 2023 Dec 18;11(12):3348. doi: 10.3390/biomedicines11123348

Table 5.

Kinetic parameters obtained from NE and NLC curcumin release profiles.

Correlation Coefficient (r2) Residual Sum of Squares K (72 h) 1
NE-CUR NLC-CUR NE-CUR NLC-CUR NE-CUR NLC-CUR
Zero order 0.94 0.98 156.54 21.66 - -
First order 0.97 0.99 0.0152 0.002 - -
Higuchi 0.99 0.99 20.46 8.47 0.04 0.036

1 The value of K was determined considering the Higuchi model for both formulations.