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. 2023 Dec 7;15(24):5741. doi: 10.3390/cancers15245741
Diagnosis Details
Diagnosis Details
4.1.1 Date of HCC diagnosis Date
4.1.2 Mode of HCC Diagnosis Radio
1, Histopathology (includes biopsy, surgical resection)|2, Imaging
4.1.3 Histology type Dropdown
1, Biopsy|2, Surgical Specimen
4.1.4 Imaging type Radio
1, Multiphase CT|2, MRI Liver|3, CEUS|4, Other: clinical: {dx_other}
4.1.5 Other mode of diagnosis Text
4.1.6 Method or presentation of HCC Diagnosis Radio
1, Screening/surveillance—please specify reason for doing so: {dx_screen_reason}|2, Incidental—please specify how so: {dx_incident_how}|3, Symptoms|4, Other: {dx_other_method}
4.1.7 Reason for screening/surveillance Text
4.1.8 Incidental (how) Text
4.1.9 Other (method or presentation) Text
4.1.10 Tumour Size (largest lesion measured in cm) Text
4.1.11 Site of the largest lesion(s) Checkbox
1, dx_largelesion_location___1 Seg 1 (caudate lobe)|2, dx_largelesion_location___2 Seg 2|3, dx_largelesion_location___3 Seg 3|4, dx_largelesion_location___4 Seg 4a|5, dx_largelesion_location___5 Seg 4b|6, dx_largelesion_location___6 Seg 5|7, dx_largelesion_location___7 Seg 6|8, dx_largelesion_location___8 Seg 7|9, dx_largelesion_location___9 Seg 8|10, dx_largelesion_location___10 Diffuse type not easily determined|11, dx_largelesion_location___11 Right lobe (segment not specified)|12, dx_largelesion_location___12 Left lobe (segment not specified)|13, dx_largelesion_location___13 None of the above|-99, dx_largelesion_location____99 Not recorded
4.1.12 Number of HCC lesions Text
4.1.13 Total Lobes with lesion(s) Dropdown
1, one lobe only|2, both lobes|-99, unknown site of lesion(s)
4.1.14 Child Pugh Class Dropdown
1, A (5–6)|2, B (7–9)|3, C (10–15)|-99 Unknown—unknown result
4.1.15 You have selected: [dx_childpugh_class] This equates to: [calc_childpugh_c2s] Descriptive
4.1.16 Calculation—Class to Score Text
4.1.17 Child–Pugh Score Text
4.1.18 You have selected: [dx_childpugh_score] This equates to: [calc_childpugh_s2c] Descriptive
4.1.19 Calculation- Score to Class Text
4.1.20 BCLC Staging Score Dropdown
0, 0—Very early (single < 2 cm)|1, A—Early (single, 3 nodules ≤ 3 cm)|2, B—Intermediate (multinodular)|3, C—Advanced (portal invasion)|4, D—End-stage|-99, Unknown—Unknown result
4.1.21 Other comorbidities Dropdown
1, Yes—see next field for details|2, No—no other known comorbidities
4.1.22 Charlson Comorbidity Index Checkbox
1, dx_comorbidet___1 Prior myocardial infarction|2, dx_comorbidet___2 Congestive heart failure|3, dx_comorbidet___3 Peripheral vascular disease|4, dx_comorbidet___4 Cerebrovascular disease or Transient ischemic attack (TIA)|5, dx_comorbidet___5 Dementia|6, dx_comorbidet___6 Chronic obstructive pulmonary disease|7, dx_comorbidet___7 Rheumatologic disease or Connective tissue disease|8, dx_comorbidet___8 Peptic ulcer disease|9, dx_comorbidet___9 Mild liver disease|10, dx_comorbidet___10 Moderate or severe liver disease (severe = cirrhosis and portal hypertension with variceal bleeding history, moderate = cirrhosis and portal hypertension but no variceal bleeding history, mild = chronic hepatitis (or cirrhosis without portal hypertension))|11, dx_comorbidet___11 Diabetes with chronic complications|12, dx_comorbidet___12 Cerebrovascular (hemiplegia) event|13, dx_comorbidet___13 Moderate-to-severe chronic renal/kidney disease (severe = on dialysis, status post-kidney transplant, uraemia, moderate = creatinine > 3 mg/dL (0.27 mmol/L))|14, dx_comorbidet___14 Cancer without metastases/localised solid tumour|15, dx_comorbidet___15 Metastatic solid tumour|16, dx_comorbidet___16 Leukaemia|17, dx_comorbidet___17 Lymphoma|18, dx_comorbidet___18 Acquired immunodeficiency syndrome (AIDS)|19, dx_comorbidet___19 Other: {dx_other_comorbidity}|20, dx_comorbidet___20 Atrial fibrillation (AF)/Supraventricular tachycardia (SVT)|21, dx_comorbidet___21 Uncomplicated diabetes|22, dx_comorbidet___22 None of the above|-99, dx_comorbidet____99 Unknown
4.1.23 Other comorbidity Text
4.1.24 Diabetes at time of diagnosis Dropdown
0, No—did not have diabetes|1, T1DM—had type 1 diabetes mellitus|2, T2DM—had type 2 diabetes mellitus (NIDDM)|3, T2IDM—had type 2 insulin-dependent diabetes mellitus (IDDM)|4, Yes—unspecified—known to have diabetes but specific type missing|-99, Unknown—diabetes status unknown
4.1.25 Portal hypertension Dropdown
1, Yes—had portal hypertension at diagnosis|2, No—did not have portal hypertension at time of diagnosis|-99, Unknown
4.1.26 AFP measured Text
4.1.27 AFP result—unit of measurement Dropdown
1, μg/mL|2, ng/mL or μg/L|3, Other|-99, Unknown—units unknown
4.1.28 Platelets ×109/L Text
4.1.29 Albumin Text
4.1.30 Other AFP Unit Measurement Text
4.1.31 ECOG at time of diagnosis Dropdown
0, 0 = Fully active, able to carry on all pre-disease performance without restriction|1, 1 = Restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature, e.g., light house work, office work|2, 2 = Ambulatory and capable of all self-care but unable to carry out any work activities; up and about more than 50% of waking hours|3, 3 = Capable of only limited self-care; confined to bed or chair more than 50% of waking hours|4, 4 = Completely disabled; cannot carry on any selfcare; totally confined to bed or chair|5, 5-Dead|-99, ECOG not documented
4.1.32 Presence of Ascites Radio
1, Yes|2, No|-99, Not recorded
4.1.33 Presence of hepatic encephalopathy Radio
1, Yes|2, No|-99, Not recorded
Form Status
4.2.1 Complete? Dropdown
0, Incomplete|1, Unverified|2, Complete