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. 2023 Dec 18;11(12):3342. doi: 10.3390/biomedicines11123342

Figure 1.

Figure 1

Study design and limiting infarct volume and brain edema in ipsilateral ischemic brain under hyperglycemia in LA-treated animals. (A) A description of the study design with time points that represent various stages of ischemic stroke: acute (post-24 h), sub-acute (day 3), moderate (day 5), and chronic (day 7). (B–E) Silver-stained quantification showing LA limiting the infarct volume in hyperglycemic animals after 24 h, 3, 5, and 7 days following ischemic stroke, compared to the normoglycemic and respective controls. (F–I) Brain edema attenuation in LA-treated hyperglycemic ischemic-stroke animals at four time points; the values presented are the mean ± SD. The analysis was performed using ordinary one-way ANOVA and Tukey’s multiple comparisons test (B–I). * p < 0.05; ** p < 0.01.