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Representative histology of the spinal cords in EAE mice. G3: Cross-section from MAP2 Immunohistochemistry spinal cord staining. EAE mice received a daily IP injection of PEPITEM (G3) until day 21 post-EAE induction. There is patchy vacuolation (O) in the white matter. There is no significant lymphocytic inflammation in leptomeninges (*). The neurons of anterior horn are present and diffusely stained (^), (n = 3).
