Figure 2.

New insights and hypotheses regarding the molecular and cellular processes in the vicious circle that would trigger the pathophysiological manifestations in LC. The arrows indicate the closing of the dangerous circle that self-maintains and amplifies the inflammatory phenomena (Figure 2 was imagined and drawn by L.M.A. using Microsoft Paint 3D for Windows 10 being modified and drawn by the same main author, L.M.A. [121]).