Figure 3.

Mitochondrial dysfunction in LC correlated with the synergistic interaction between infection, gut dysbiosis, systemic inflammation, dysregulated immune system, molecular mimicry, and auto-immunity, generating a vicious self-sustained circle and reflecting molecular and cellular processes from “leaky gut” to “leaky ETC” in a quantum leap. The arrows indicate the closing of the dangerous circle that self-maintains and amplifies the inflammatory phenomena (Figure 3 was imagined and drawn by L.M.A. using Microsoft Paint 3D for Windows 10 and using completely free picture material from SeekPNG.com (accessed on 26 October 2023), for which we are very grateful), being modified after Figure 2 [121]).