. 2023 Dec 18;24(24):17624. doi: 10.3390/ijms242417624

Table 2.

Differentially expressed genes involved in NUE-related traits in flax functionally that have been validated in other plant studies.

Flax DEG	Gene Name	Protein Name	QTL	Trait	Function	Up/Down (Log₂FC)	Reference
Lus10027573	CRF4	Ethylene-responsive transcription factor CRF4	Not in QTL	Unknown	N signaling	Up LN (1.20)	[49]
Lus10029683	NRG2	Nitrate regulatory gene2 protein	Lu9_18443162	RV_Index	N signaling	Down LN (−1.33)	[50]
Lus10019292	LBD38	LOB domain-containing protein 38	Not in QTL	Unknown	NO₃⁻ response regulation	Up LN (1.27)	[51]
Lus10038783	KINB2	SNF1-related protein kinase regulatory subunit beta-2	Lu11_1841121	NUE_N−, NUE_N+, NUE_STI	NO₃⁻ assimilation	Down LN (−1.32)	[52]
Lus10041466	NPF3.1	Protein NRT1/PTR FAMILY 3.1	Lu4_14298191	R/S_N−	NO₃⁻ assimilation	Up LN (1.49)	[53]
Lus10035402	NIA	Nitrate reductase [NADH]	Not in QTL	Unknown	NO₃⁻ assimilation	Down LN (−1.26)	[54]
Lus10027270	NR	Nitrate reductase [NADH]	Not in QTL	Unknown	NO₃⁻ assimilation	Down LN (−1.46)	[55]
Lus10004037	GS1-2	Glutamine synthetase cytosolic isozyme 2	Not in QTL	Unknown	NH₄⁺ assimilation	Down LN (−1.37), Down HN (−1.03)	[56]
Lus10029256	CEP14	Precursor of CEP14	Not in QTL	Unknown	NH₄⁺ assimilation, root development	Down LN (−1.16)	[57]
Lus10016120	NRT2.1	High-affinity nitrate transporter 2.1	Not in QTL	Unknown	NO₃⁻ transporter	Down LN (−1.17)	[58]
Lus10030902	NRT2.5	High affinity nitrate transporter 2.5	Lu13_18363934	RT_Index, R/S_N+	NO₃⁻ transporter	Down LN (−2.38), Down HN (−1.83)	[59]
Lus10014537	NPF1.1	Protein NRT1/PTR FAMILY 1.1	Not in QTL	Unknown	NO₃⁻ transporter	Up LN (1.12)	[18]
Lus10032876	NPF4.6	Protein NRT1/PTR FAMILY 4.6	Not in QTL	Unknown	NO₃⁻ transporter	Down LN (−1.06)	[60]
Lus10032252	NPF6.3	Protein NRT1/PTR FAMILY 6.3	Not in QTL	Unknown	NO₃⁻ transporter	Down LN (−1.21)	[58]
Lus10004760	AMT1-2	Ammonium transporter 1 member 2	Lu14_9866805	RV_N−	NH₄⁺ transporter	Down LN (−3.14), Down HN (−2.20)	[61]
Lus10008564	ACO1	1-aminocyclopropane-1-carboxylate oxidase 1	Lu11_14898826	NUE_N−	Root development	Up LN (1.04)	[62]
Lus10036251	GSO1	LRR receptor-like serine/threonine-protein kinase GSO1	Lu12_1386203	RT_N+, R/S_N−	Root development	Up LN (1.91)	[63]
Lus10016554	FLA4	Fasciclin-like arabinogalactan protein 4	Lu12_4334157	PDW_N+	Root development	Down LN (−1.02)	[64]
Lus10011346	WRKY75	Probable WRKY transcription factor 75	Lu13_19862281	TRL_Index	Root development	Up LN (1.46)	[65]
Lus10042154	FH8	Formin-like protein 8	Lu14_15927781	RV_N+	Root development	Up LN (1.53)	[66]
Lus10021428	MYB36	Transcription factor MYB36	Lu14_3980668	R/S_N−	Root development	Down LN (−1.02)	[67]
Lus10035126	RPK2	LRR receptor-like serine/threonine-protein kinase RPK2	Lu2_21668160	PDW_N+	Root development	Down LN (−1.28)	[63]
Lus10024314	BZIP29	bZIP transcription factor 29	Lu6_17695007	NUE_N+, R/S_N+	Root development	Down LN (−1.06)	[68]
Lus10024908	NAC021	NAC domain-containing protein 21/22	Lu9_19469655	R/S_N−, RV_Index	Root development	Up LN (1.20)	[69]
Lus10031059	MIZ1	Protein MIZU-KUSSEI 1	Lu9_6368499	NUE_N+	Root development	Down LN (−1.54), Down HN (−1.40)	[70]
Lus10012461	CEPR2	Receptor protein-tyrosine kinase CEPR2	Not in QTL	Unknown	Root development	Up LN (1.08)	[71]
Lus10010238	MYB77	Transcription factor MYB77	Not in QTL	Unknown	Root development	Down LN (−1.22)	[72]
Lus10040274	LBD29	LOB domain-containing protein 29	Not in QTL	Unknown	Root development	Up LN (1.80)	[73]
Lus10025455	ACR4	Serine/threonine-protein kinase-like protein ACR4	Not in QTL	Unknown	Root development	Up LN (1.63)	[74]
Lus10040592	SUNN	Leucine-rich repeat receptor-like kinase protein SUNN	Not in QTL	Unknown	Root development	Down LN (−1.32)	[75]
Lus10017271	ABCB19	ABC transporter B family member 19	Not in QTL	Unknown	Root development	Up LN (1.52)	[76]
Lus10010012	ABCB4	ABC transporter B family member 4	Not in QTL	Unknown	Root development	Down LN (−1.06)	[77]
Lus10005574	CAT8	Cationic amino acid transporter 8	Lu14_17132252	R/S_N+	Amino acid transport	Up LN (1.15)	[78]
Lus10020181	GGCT2.1	Gamma-glutamylcyclotransferase 2.1	Lu2_4220131	TRL_Index, RT_Index	Amino acid transport	Up LN (1.38)	[79]
Lus10029533	BAT1	Amino-acid permease BAT1 homolog	Not in QTL	Unknown	Amino acid transport	Up LN (1.12)	[80]
Lus10012824	AVT1J	Amino acid transporter AVT1J	Not in QTL	Unknown	Amino acid transport	Up LN (1.72)	[81]
Lus10008910	GDU5	Protein GLUTAMINE DUMPER 5	Not in QTL	Unknown	Amino acid transport	Down LN (−1.20), Down HN (−1.99)	[82]
Lus10042740	AAP3	Amino acid permease 3	Not in QTL	Unknown	Amino acid transport	Down LN (−1.49)	[83]
Lus10011451	BAC2	Mitochondrial arginine transporter BAC2	Not in QTL	Unknown	Amino acid transport	Down LN (−1.23)	[84]
Lus10015513	GDU3	Protein GLUTAMINE DUMPER 3	Not in QTL	Unknown	Amino acid transport	Down LN (−1.19)	[85]

LN: low NUE genotype; HN: high NUE genotype.