Table 3.
Results of univariate analyses conducted using the Cox regression model to assess the predictors of poor outcomes, including local recurrence and metastasis, for cutaneous squamous cell carcinomas in solid organ transplant patients.
| Variable | HR | CI (95%) | p-Value |
|---|---|---|---|
| Sex | 2.69 | (0.6–10.8) | NS |
| Age (years) | 1.01 | (0.9–1.0) | NS |
| SCC location | 0.06 | (0.0–6.3) | NS |
| Tumor diameter (>2 cm) | 3.06 | (2.2–4.3) | 0.001 |
| Depth of invasion (>4 mm) | 5.06 | (1.07–2.8) | 0.040 |
| Clark level of invasion | 3.7 | (1.3–10.4) | 0.011 |
| Histologic differentiation | 2.48 | (0.8–7.4) | NS |
| Perineural invasion | 2.69 | (0.5–13.0) | NS |
| Limphovascular invasion | 1.0 | (0.0–7.3) | NS |
| Margin status | 1.2 | (0.3–5.17) | NS |
HR: Hazard ratio; CI: confidence interval; NS: Non-significant (p > 0.05).