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. 2023 Dec 15;24(24):17501. doi: 10.3390/ijms242417501

Figure 4.

Figure 4

SAA deficiency exacerbates lung injury in sepsis. Plasma creatinine levels in WT and SAA-TKO mice (A) 24 h after CLP (B) 24 h after a sublethal dose of LPS. (C) Representative H&E stained lung sections from male, M, and female, F, WT and SAA-TKO mice (n = 4/sex/strain) 24 h after CLP as described under “Section 4”. Scale bar represents 100 μm. (D) Compliance and (E) inspiratory capacity of the lungs of WT and SAA-TKO mice 24 h after CS treatment, measured using the FlexiVent system as described under “Section 4”. Data are mean ± SEM. * = p < 0.05; and ** = p < 0.01.