Table 1.
Baseline demographic and clinical characteristics of patients.
| Variable | Total (n = 226) | Pre-BMCB (n = 33) | Post-BMCB (n = 193) | p-Value |
|---|---|---|---|---|
| Mean age, years (range) | 66.0 (24–92) | 61.8 (31–84) | 66.8 (24–92) | 0.028 ‡ |
| Male sex, n (%) | 140 (61.9%) | 22 (66.7%) | 118 (61.1%) | 0.690 * |
| Mean Katagiri score (range) | 5.0 (0–9) | 5.2 (1–8) | 5.1 (0–9) | 0.786 ‡ |
| Mean Tokuhashi score (range) | 6.1 (1–13) | 6.1 (2–12) | 6.1 (1–13) | 0.746 ‡ |
| Mean SINS (range) | 10.5 (2–18) | 9.7 (3–16) | 10.7 (2–18) | 0.069 ‡ |
| Pre-radiation, n (%) | 61 (27.0%) | 5 (15.2%) | 56 (29.0%) | 0.136 * |
| Pre-chemotherapy, n (%) | 104 (46.0%) | 16 (48.5%) | 88 (45.6%) | 0.851 * |
| Mean operating time, min (range) | 201 (59–1735) | 229 (53–440) | 196 (59–1735) | 0.025 ‡ |
| Mean blood loss, mL (range) | 327 (0–2500) | 295 (0–1400) | 332 (0–2500) | 0.748 ‡ |
| Mean hospital stay, days (range) | 25.3 (0–430) | 54.8 (10–353) | 20.3 (0–430) | <0.001 ‡ |
| Operation | ||||
| Posterior stabilization | 46 | 1 | 45 | |
| Posterior decompression | 20 | 9 | 11 | |
| Posterior decompression and stabilization | 160 | 23 | 137 | |
| ECOGPS grade, n | 0.127 † | |||
| PS1 | 20 | 2 | 18 | |
| PS2 | 35 | 3 | 32 | |
| PS3 | 74 | 9 | 65 | |
| PS4 | 97 | 19 | 78 | |
| Mean BI (range) | 54.2 (0–100) | 44.1 (5–100) | 56.0 (0–100) | 0.049 ‡ |
| Frankel classification, n (%) | >0.999 * | |||
| Grade A, B, and C | 94 (41.6) | 14 (42.4) | 80 (41.5) | |
| Grade D and E | 132 (58.4) | 19 (57.6) | 113 (58.5) |
* Fisher’s exact test; † Chi-square test; ‡ Mann–Whitney U test. Abbreviations: BMCB, bone metastasis cancer board; SINS, spinal instability neoplastic score; ECOGPS, eastern cooperative oncology group performance status; BI, Barthel index.