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. 2023 Dec 10;13(12):1698. doi: 10.3390/jpm13121698

Table 1.

Current therapeutic intervention in ALC.

Therapeutic Intervention for ALC Mechanism of Action Benefits Limitations
Nutritional Therapy Provides essential nutrients to support liver function and prevent malnutrition. Improves overall health and reduces the risk of complications. May not be effective in advanced stages of cirrhosis.
Abstinence from Alcohol Prevents further liver damage and allows for liver regeneration. Essential for long-term survival and improvement of liver function. May be difficult to achieve for individuals with alcohol dependence.
Diuretics Reduce fluid accumulation in the abdomen (ascites) and legs (edema). Improves quality of life and reduces symptoms such as abdominal discomfort and shortness of breath. May cause electrolyte imbalances and dehydration.
Lactulose Prevents and treats hepatic encephalopathy, a complication of cirrhosis that causes confusion and impaired mental function. Improves neurologic function and reduces the risk of coma. May cause diarrhea and abdominal discomfort.
Antibiotics Prevent and treat bacterial infections, which are more common in individuals with cirrhosis. Reduces the risk of serious infections that can worsen liver function. Can contribute to antibiotic resistance.
Endoscopic Therapy Treats complications of cirrhosis, such as esophageal variceal bleeding. Reduces the risk of life-threatening bleeding. May require repeated procedures.
Liver Transplantation Replaces the diseased liver with a healthy one. Cures cirrhosis and improves survival. Requires a suitable donor liver and carries the risks of surgery and immunosuppression.