Table 1.
Current therapeutic intervention in ALC.
| Therapeutic Intervention for ALC | Mechanism of Action | Benefits | Limitations |
|---|---|---|---|
| Nutritional Therapy | Provides essential nutrients to support liver function and prevent malnutrition. | Improves overall health and reduces the risk of complications. | May not be effective in advanced stages of cirrhosis. |
| Abstinence from Alcohol | Prevents further liver damage and allows for liver regeneration. | Essential for long-term survival and improvement of liver function. | May be difficult to achieve for individuals with alcohol dependence. |
| Diuretics | Reduce fluid accumulation in the abdomen (ascites) and legs (edema). | Improves quality of life and reduces symptoms such as abdominal discomfort and shortness of breath. | May cause electrolyte imbalances and dehydration. |
| Lactulose | Prevents and treats hepatic encephalopathy, a complication of cirrhosis that causes confusion and impaired mental function. | Improves neurologic function and reduces the risk of coma. | May cause diarrhea and abdominal discomfort. |
| Antibiotics | Prevent and treat bacterial infections, which are more common in individuals with cirrhosis. | Reduces the risk of serious infections that can worsen liver function. | Can contribute to antibiotic resistance. |
| Endoscopic Therapy | Treats complications of cirrhosis, such as esophageal variceal bleeding. | Reduces the risk of life-threatening bleeding. | May require repeated procedures. |
| Liver Transplantation | Replaces the diseased liver with a healthy one. | Cures cirrhosis and improves survival. | Requires a suitable donor liver and carries the risks of surgery and immunosuppression. |