Table 1.
Main patient features at RC stratified by SII group.
| Characteristic | Total | Low SII | High SII | p |
|---|---|---|---|---|
| N = 193 | N = 80 (41.4) | N = 113 (58.5) | ||
| Age, n (%) | 0.82 | |||
| <70 | 30 (15.5) | 13 (12.4) | 17 (17.6) | |
| ≥70 | 163 (84.4) | 67 (67.6) | 96 (95.4) | |
| Sex, n (%) | 0.06 | |||
| Male | 154 (79.7) | 69 (86.2) | 85 (75.2) | |
| Female | 39 (20.2) | 11 (13.7) | 28 (24.7) | |
| Smoke, n (%) | 149 (77.2) | 65 (81.2) | 84 (74.3) | 0.25 |
| Diabetes, n (%) | 31 (16.0) | 13 (16.2) | 18 (15.9) | 0.95 |
| Clinical T stage, n (%) | 0.009 | |||
| cTa | 67 (34.7) | 32 (40.0) | 35 (30.9) | |
| cTis | 24 (12.4) | 14 (17.5) | 10 (8.8) | |
| cT1 | 49 (25.3) | 19 (23.7) | 30 (26.5) | |
| cT2 | 29 (15.0) | 13 (16.2) | 16 (14.1) | |
| cT3 | 18 (9.3) | 2 (2.5) | 16 (14.1) | |
| cT4 | 6 (3.1) | 0 (0.0) | 6 (5.3) | |
| BMI, median (IQR) | 26 (24–29) | 27 (25–29) | 26 (24–28) | 0.04 |
| Surgical approach, n (%) | 1.00 | |||
| Open | 186 (96.3) | 77 (96.2) | 109 (96.4) | |
| Robot-assisted | 7 (3.6) | 3 (3.7) | 4 (3.5) | |
| Urinary diversion, n (%) | 0.005 | |||
| Ureterocutaneostomy | 21 (10.8) | 6 (7.5) | 15 (13.2) | |
| Ileal conduit | 148 (76.6) | 57 (71.2) | 91 (80.5) | |
| Orthotopic neobladder | 24 (12.4) | 17 (21.2) | 7 (6.1) | |
| Pathological T stage, n (%) | 0.005 | |||
| pT0 | 14 (7.2) | 6 (5.8) | 8 (8.2) | |
| pTa | 10 (5.1) | 4 (4.1) | 6 (5.9) | |
| pTis | 23 (11.9) | 14 (9.5) | 9 (13.5) | |
| pT1 | 26 (13.4) | 17 (10.8) | 9 (15.2) | |
| pT2a | 30 (15.5) | 10 (12.4) | 20 (17.6) | |
| pT2b | 5 (2.5) | 3 (2.1) | 2 (2.9) | |
| pT3a | 49 (25.3) | 21 (20.3) | 28 (28.7) | |
| pT3b | 8 (4.1) | 1 (3.3) | 7 (4.7) | |
| pT4a | 21 (10.8) | 4 (8.7) | 17 (12.3) | |
| pT4b | 7 (3.6) | 0 (2.9) | 7 (4.1) | |
| N, n (%) | 37 (19.1) | 7 (8.7) | 30 (26.5) | 0.002 |
| LVI, n (%) | 128 (66.3) | 44 (55.0) | 84 (74.3) | 0.005 |
| Locally advanced disease, n (%) | 102 (52.8) | 30 (37.5) | 72 (63.7) | <0.001 |
| Adjuvant chemotherapy, n (%) | 40 (20.7) | 14 (17.5) | 26 (23.0) | 0.35 |
| Progressive disease, n (%) | 61 (31.6) | 17 (21.2) | 44 (38.9) | 0.009 |
| Any-cause deaths, n (%) | 96 (49.7) | 32 (40.0) | 64 (56.6) | 0.02 |
| Cancer-related deaths, n (%) | 52 (26.9) | 18 (22.5) | 34 (30.0) | 0.24 |
SII = Systemic immune-inflammation index; BMI = Body mass index; IQR = Interquartile range; LVI = Lymph vascular involvement; N = Lymph node invasion. Bold: emphasise the statistical correlation between the calculations.