Table 2.
Multivariate logistic regression analyses predicting oncological outcomes.
| Characteristic | OR | N | Advanced pT Stage | Locally Advanced Condition | |||||
|---|---|---|---|---|---|---|---|---|---|
| 95% CI | p-Value | OR | 95% CI | p-Value | OR | 95%CI | p-Value | ||
| SII (Reference:low) | |||||||||
| High | 2.86 | 1.07, 7.59 | 0.035 | 2.17 | 1.00, 4.78 | 0.048 | 2.81 | 1.37, 5.76 | 0.005 |
| Age | 1.10 | 0.94, 1.04 | 0.89 | 0.83 | 0.31, 2.26 | 0.728 | 1.05 | 0.41, 2.67 | 0.90 |
| Smoke (Reference: no) | |||||||||
| Smoke | 0.56 | 0.22, 1.41 | 0.21 | 0.67 | 0.26, 1.67 | 0.392 | 1.28 | 0.52, 3.14 | 0.57 |
| Sex (Reference: male) | |||||||||
| Female | 0.53 | 0.18, 1.52 | 0.23 | 0.25 | 0.08, 0.80 | 0.019 | 0.52 | 0.19, 1.38 | 0.19 |
| Clinical tumor stage | |||||||||
| (Reference: cTa/cTis/cT1) | |||||||||
| cT2 | 5.38 | 1.97, 14.62 | 0.001 | 56.10 | 11.42, 275.61 | <0.001 | 31.06 | 6.68, 144.34 | <0.001 |
| cT3/cT4 | 10.69 | 3.75, 30.47 | <0.001 | 33.42 | 6.78, 164.58 | <0.001 | |||
| Goodness-of-fit test | Hosmer–Lemeshow test | 0.89 | 0.18 | 0.85 | |||||
| AUC | |||||||||
| Model with SII | AUC: 0.79 | AUC: 0.81 | 0.26 | AUC: 0.81 | |||||
| Model without SII | AUC: 0.76 (+3%) | AUC: 0.79 (+2%) | AUC: 0.76 (+5%) | ||||||
| (p = difference model) | 0.19 | 0.13 | 0.04 | ||||||
SII = Systemic immune-inflammation index; N = Lymph node invasion; OR = Odds ratio; CI = Confidence interval; AUC = Area under the curve. Bold: emphasise the statistical correlation between the calculations.