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(A) (A-1) Identified lipid droplet accumulation inhibitors (LDAI) from food origin. (A-2) Design strategy for a β-carboline alkaloid using naturally occurring amino acid and phenolic aldehyde precursors. (B) Chemo-selective derivatization of vanilla beans (BE8s) and dereplication strategy in the modified bean extract (CBE8). (C) Chemical preparation of 34 for the LDAI assay and proposed fragmentation pathway.
