Table 5.
rpoB gene amino acid substitutions associated with rifabutin-resistant H. pylori strains.
No. | Strain Name | MIC µg/uL | rpoB Mutation | |||||
---|---|---|---|---|---|---|---|---|
E470 | D530 | V538 | R701 | L2196 | A2710 | |||
1 | Ke9 | 8 | G | P | V | |||
2 | UB217 | 4 | N | C | ||||
3 | UB75 | 0.12 | I | |||||
4 | Kh67 | 0.06 | I | |||||
Sensitive stains (n = 217) < 0.12 | E | D | V | R | L | A |
E, glutamic acid; N, asparagine; D, aspartic acid; V, valine; R, arginine; L, leucine; A, alanine; G, glycine; I, isoleucine; C, cysteine. Green indicates resistance. Blue indicates the corresponding, previously reported mutation; light green indicates new hypothetical mutations. UB, Ulaanbaatar capital city; Ke, Khentii; Kh, Khuvsgul.