Simulation of IAV–streptococcus coinfection according to the model in Smith and Smith [85] varying time of secondary infection. Target cells (“T”, panel (A)) that become infected enter an eclipse phase (“I1”, panel (B)), transition to producing IAV (“I2”, panel (C)), and are eventually cleared. IAV (“V”, panel (D)) is administered at time 0. Streptococcus (“P”, panel (E)) is administered at varying times of secondary infection. Time is shown in units of days. The time of secondary infection was uniformly sampled between times 5 and 9 for 1000 replicates. The inset shows colors for the time of secondary infection, from time 5 (“Low”) to time 9 (“High”).