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Effect of increased berberine (A) and β-escin (B) doses on the venous pressure (VP) of rats under anesthesia. Abscissae correspond to increased doses of the treatments. * indicates a significant difference between the control (RHL) and the values of VP of the limb with venous hypertension (LHLA) (p < 0.05 Student’s test for paired samples). The symbols represent the mean ± SEM (standard error of the mean) of eight experiments using berberine and six using β-escin.
