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. 2023 Dec 14;12(12):1452. doi: 10.3390/pathogens12121452

Figure 3.

Figure 3

Sex difference in local macrophages and granulocytes was found. Significantly higher levels of macrophages in spleen of both male and female Stat1ko mice (A) when compared to corresponding B6 and CCR2ko (* for male, # for female, p < 0.05, Mann–Whitney rank sum test). More Ly6G+ cells in the spleen were found in Stat1ko females when compared to the corresponding males. Interestingly, higher levels of macrophages were found in infected tongues (B) of B6 female mice when compared to corresponding B6 males ((B), * p < 0.05, Mann–Whitney rank sum test). More Ly6G+ granulocytes in the spleen were found in Stat1ko females when compared to the corresponding males ((C), * p < 0.05, Mann–Whitney rank sum test). A sex difference was not found in the infected tongue of B6 mice for Ly6G+ granulocytes ((D), * p > 0.05, Mann–Whitney rank sum test). Significantly higher levels of Ly6G+ granulocytes were found in CCR2ko males when compared to corresponding B6 females (p < 0.05, Mann–Whitney rank sum test).