Figure 6.

Viral transcripts (A) in the infected tongues and anti-MmuPV1 E4 IgG (B,C) in the sera of MmuPV1-infected BALB/C and FVB mice. BALB/C and FVB mice were tested for infection in the tongue. Similar levels of viral transcripts were found in both male and female mice for both strains (A). Similar to what we observed in other mice, significantly higher levels of anti-MmuPV1 E4 isotype IgG3 were found in females of BALB/c ((B), * p = 0.0395, Mann–Whitney rank sum test) and FVB ((C), * p < 0.01, Mann–Whitney rank sum test) when compared to the corresponding males. No significant difference was found in anti-MmuPV1 E4 isotype IgM between mouse strains.