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. 2023 Dec 8;28(24):8018. doi: 10.3390/molecules28248018

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Relative lesional radiotracer uptake at the different time points represented as ‘waterfall’ plots of the percentage variation (%Δ1/2/3) of the tumour-to-background ratio (TBR). We only included patients who completed at least visit 1 and 3 scans within this analysis to avoid bias. The variations were evaluated as follows: %Δt1 = ((t2 − t1)/t1) × 100, n = 28 lesions; %Δt2 = ((t3 − t1)/t1) × 100, n = 48 lesions; %Δt3 = ((t3 − t2)/t2) × 100), n = 28 lesions. TBRBoneMet = SUV_maxBoneMet/SUV_meanBackgBone. TBRSoftTissueMet = SUV_maxSoftTissueMet/SUV_meanBackgMuscle (Backg: background). Soft-tissue metastases are identified with black-outlined bars (rest are bone metastases). Subject P02 is classified as partial responder based on PCWG3.