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Inhibitor studies: Compound 11h in HG-3 and PGA-1 CLL cell lines—Annexin V/PI FACS analysis (48 h). The HG-3 and PGA-1 CLL cells (5 × 104 cells/mL) were pre-treated at 37 °C with either 5 mM N-acetylcysteine (NAC) for 1 h or 40 μM caspase inhibitor C (Z-VAD-FMK) for 4 h prior to 5 μM compound treatment for 48 h.
