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. 2023 Dec 14;28(24):8095. doi: 10.3390/molecules28248095

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Preliminary cell viability data for nitrovinylanthracenes and related compounds in CLL: (A) HG-3 cells (1 and 10 μM) and (B) PGA-1 cells (1 and 10 μM). Cell proliferation of HG-3 and PGA-1 cells was determined with an alamarBlue assay. Compound concentrations of either 1 μM or 10 μM for 24 h were used to treat the cells (in triplicate) with control wells containing vehicle ethanol (1% v/v). Map = maprotiline, Flu = fludarabine The mean value for three experiments is shown. Statistical significance was evaluated using the Kruskal–Wallis test. * Indicates a p value between 0.01 and 0.05; ** indicates a p value between 0.001 and 0.01.

Preliminary cell viability data for nitrovinylanthracenes and related compounds in CLL: (A) HG-3 cells (1 and 10 μM) and (B) PGA-1 cells (1 and 10 μM). Cell proliferation of HG-3 and PGA-1 cells was determined with an alamarBlue assay. Compound concentrations of either 1 μM or 10 μM for 24 h were used to treat the cells (in triplicate) with control wells containing vehicle ethanol (1% v/v). Map = maprotiline, Flu = fludarabine The mean value for three experiments is shown. Statistical significance was evaluated using the Kruskal–Wallis test. * Indicates a p value between 0.01 and 0.05; ** indicates a p value between 0.001 and 0.01.