TABLE 2.
Genes dysregulated in the ∆dcm mutant relative to WT
| Locus tag | Gene name | Description | EXP fold change | ES fold change |
|---|---|---|---|---|
| Metabolism | ||||
| ID870_08455 | treP | Trehalose phosphorylase | 69.17 | 2.75 |
| ID870_08450 | treC | Trehalose-6-phosphate hydrolase | 66.48 | 3.00 |
| ID870_00285 | lacA | Galactose-6-phosphate subunit A | 4.12 | 5.40 |
| ID870_00290 | lacB | Galactose-6-phosphate subunit B | 3.42 | 2.82 |
| ID870_01490 | dhaK | Dihydroxyacetone kinase subunit K | 9.46 | 18.97 |
| ID870_01485 | dhaL | Dihydroxyacetone kinase subunit L | 9.42 | 19.20 |
| ID870_01480 | dhaM | Dihydroxyacetone kinase subunit M | 5.38 | 20.00 |
| ID870_04305 | cstA | Carbon starvation protein A | 1.61 | 31.37 |
| ID870_10075 | argF | Ornithine carbamoyltransferase | 1.16 | 10.30 |
| ID870_10080 | arcC | Carbamate kinase | 1.17 | 7.80 |
| ID870_00265 | PTS sugar transporter subunit IIA | 4.08 | 2.85 | |
| ID870_00270 | PTS sugar transporter subunit IIB | 3.53 | 2.27 | |
| ID870_00275 | PTS galactitol transporter subunit IIC | 2.46 | 1.11 | |
| ID870_00200 | PTS mannose/fructose/sorbose transporter family subunit IID | 1.02 | 6.68 | |
| ID870_07955 | tkt | Transketolase | 1.13 | 2.96 |
| ID870_08425 | Transketolase | 1.04 | 5.04 | |
| ID870_08430 | Transketolase | 1.03 | 4.82 | |
| ID870_01010 | fsa | Fructose-6-phosphate aldolase | 1.07 | 2.27 |
| ID870_00605 | PTS ascorbate transporter subunit IIB | 1.47 | 2.64 | |
| ID870_08440 | PTS ascorbate transporter subunit IIB | 1.16 | 8.94 | |
| ID870_08435 | PTS ascorbate transporter subunit IIC | 1.41 | 5.86 | |
| Regulators | ||||
| ID870_00330 | TCS-15 response regulator | 1.18 | 2.33 | |
| ID870_03010 | TCS-12 HAMP domain-containing histidine kinase | 1.27 | 2.34 | |
| ID870_08970 | hrcA | Heat-inducible transcriptional repressor | 2.04 | 36.43 |
| ID870_00850 | MerR family transcriptional regulator | 1.27 | 3.95 | |
| ID870_02905 | DeoR/GlpR transcriptional regulator | 1.08 | 7.26 | |
| ID870_00260 | DeoR/GlpR transcriptional regulator | 1.71 | 8.32 | |
| ID870_01280 | LacI family DNA-binding transcriptional regulator | 1.19 | 2.59 | |
| ID870_04400 | Spx/MgsR family RNA polymerase-binding regulatory protein | 1.12 | 2.98 | |
| ID870_07170 | AraC family transcriptional regulator | 1.11 | 2.45 | |
| ID870_09330 | MurR/RpiR family transcriptional regulator | 1.70 | 2.72 | |
| ID870_10525 | Helix-turn-helix transcriptional regulator | 1.31 | 2.38 | |
| ID870_02005 | mtsR | Metal-dependent transcriptional regulator | 1.09 | 4.16 |
| ID870_07140 | sczA | MerR family transcriptional regulator | 1.07 | 3.50 |
| ID870_07405 | copY | CopY/TcrY family copper transport repressor | 1.38 | 17.43 |
| Metal transport | ||||
| ID870_02010 | mtsA | Metal ABC transporter substrate-binding protein | 1.14 | 18.30 |
| ID870_02015 | mtsB | Metal ABC transporter ATP-binding protein | 1.33 | 17.77 |
| ID870_02020 | mtsC | Metal ABC transporter permease | 1.72 | 16.42 |
| ID870_07400 | copA | Copper-translocating P-type ATPase | 1.32 | 11.26 |
| ID870_07395 | copZ | Heavy-metal-associated domain-containing protein | 1.21 | 10.28 |
| Adhesins | ||||
| ID870_06030 | PI-1 major pilin | 1.75 | 5.66 | |
| ID870_02595 | pilA | PI-2a subunit | 1.36 | 4.09 |
| ID870_02600 | pilB | PI-2a subunit | 1.27 | 2.21 |
| ID870_02615 | pilC | PI-2a subunit | 1.07 | 2.30 |
| ID870_07365 | pbsP | YSIRK signal domain/LPXTG anchor domain surface protein | 1.67 | 3.79 |
| Secretion systems | ||||
| ID870_04180 | esaA | Type VII secretion | 1.08 | 4.03 |
| ID870_04185 | essA | Type VII secretion | 1.32 | 3.47 |
| ID870_04195 | essB | Type VII secretion | 1.13 | 3.52 |
| ID870_08600 | Type II secretion system F family protein | 1.57 | 2.13 | |
| Other | ||||
| ID870_09380 | LysM peptidoglycan-binding domain-containing protein CDS | 1.00 | 6.53 | |
| ID870_00925 | Class I SAM-dependent MTase | 1.16 | 65.26 |