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Analysis of putative WalR-controlled essential genes. (A) Intersections between essentiality analysis and -omics data displayed as an UpSet plot. Members of gene sets where n < 8 are shown. RNA-seq significance ((RNA-seq sig) FDR > 0.05, log2FC ≥ 0.585). (B) Gene expression changes of the predicted direct WalKR regulon upon WalK activation (Wt vs WalKT389A). Essential genes with predicted WalR-binding sites are highlighted.
