FIG 3.

In vivo results suggest that RecG plays a role in maintaining replication integrity in S. aureus in the presence of host NO⋅ production. C57BL/6J mice were infected subcutaneously with 10⁷ CFU of either WT LAC or the ΔrecG mutant (n = 5). A representative graph of lesion sizes measured on days 1, 3, 5, and 7 post infection is shown in A. Bacterial burden was measured by harvesting the abscess 7 days post infection and enumerating the bacteria (B). Data were analyzed via one-way analysis of variance with Tukey’s multiple comparisons test for correction.